Centru medical dedicat patologiei musculoscheletale

RadioGraphics Update: White Matter Diseases with Radiologic-Pathologic Correlation

MS remains the leading nontraumatic cause of disability in young adults, but the prognosis has improved dramatically...
pubs.rsna

Editor’s Note.—Articles in the RadioGraphics Update section provide current knowledge to supplement or update information found in full-length articles previously published in RadioGraphics. Authors of the previously published article provide a brief synopsis that emphasizes important new information such as technologic advances, revised imaging protocols, new clinical guidelines involving imaging, or updated classification schemes. Articles in this section are published solely online and are linked to the original article.

©RSNA, 2020

Introduction
Over the last few years, many publications have been developed regarding follow-up of white matter diseases and their treatment (1). This update discusses the 2017 McDonald Criteria for the Diagnosis of Multiple Sclerosis (2) and the guidelines for MRI follow-up of multiple sclerosis (MS) on the basis of risk profile and therapy. There is also new knowledge regarding neuromyelitis optica spectrum disorders (NMOSDs), particularly the detection of anti–myelin oligodendrocyte glycoprotein (MOG) antibodies (MOG-Ab) as a distinct cause of central nervous system demyelination. A brief mention of important considerations regarding other diseases is included.

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